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Melanocortin agonism has been associated with body composition outcomes that differ from those typically observed with incretin-based therapies, including preferential reductions in fat mass and more limited weight rebound (52, 58, 128)

Steps to Start Your Journey Safely If you are considering starting a weight loss program involving GLP-1 medications, being prepared for the transition is the best way to succeed

Lancet 2021;398:216072.ArticlePubMed 100

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